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              Open Access  
Copyright: The authors. This article is an open access 
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                              Original Research 
                              
                              3. Treatment 
                              protocol with progesterone, estradiol and oxytocin 
                              to improve conception rate and allows for early 
                              diagnosis of pregnancy in black bengal goat - 
                              
                              D Sengupta, S BasuVet World. 2012; 5(5): 269-273
 
                                
              doi: 
              10.5455/vetworld.2012.269-273 
                
              
              
          
 
              Abstract 
 This 
              work was performed to develop a treatment protocol that will 
              shorten the length of estrous cycle in mated goats those fail to 
              conceive, without reduction in conception rate. In experiment 1, 
              ninety goats (single parity, 1½ to 2 years age) were divided into 
              nine groups of ten goats each. On return to heat, all groups were 
              mated barring groups 1, 3 and 4. On days 3-5 of estrous, 
              progesterone was treated at the dose rate of 10 mg i.m (groups 3, 
              5 and 7) or 30 mg i.m. (groups 4, 6 and 8). Groups 7, 8 and 9 
              received estradiol (500 ìg i.m.; day 8) + oxytocin (10 IU i.m.; 
              day 9) treatment. Following treatments, the goats were observed 
              for heat and appearance of embryonic vescicles (EV) by 
              transabdominal ultrasonography. In experiment 2, group 2 (n=50) 
              was equal to group 8 of experiment 1 and group 1 (n=50) served as 
              control. The litter size and weight was recorded at birth. Early 
              progesterone treatment significantly (P<0.05) shortened the cycle 
              length in groups 3 (day 15) and 4 (day 17) respectively compared 
              to control (group 1; 21 days), whereas mated group 5 and 6 did not 
              have any difference in conception rate compared to control (group 
              2). In does of group 5 & 6, EVs were observed much earlier than 
              group 2. Estradiol + oxytocin treatment had no effect on 
              conception rate of group 8, while does of group 7 and 9 returned 
              to heat on day 12. In experiment 2, significant difference in 
              conception rate and percentage of single, double, triplet and 
              quadruplet born was observed between control and treated groups 
              while the mean litter weight born was non-significant. Thus early 
              pregnancy diagnosis can be done at by progesterone + estrogen 
              treatment that not only shortens the length of estrous cycle, if 
              the animals fail to conceive, but also improves the conception 
              rate.  Key 
              words: progesterone, estrogen, oxytocin, estrous cycle length, 
              pregnancy, Black Bengal goats 
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